Semaglutide vs tirzepatide
You are deciding between two options.
The table below lays out the structural differences — active ingredient, dosing frequency, titration length, and maximum labelled dose. These are facts from the prescribing information. How any of them performs for a specific person is not something a table can answer.
Side-by-side
Structural facts from each product’s prescribing information.
| Product | Active ingredient | Indication | Frequency | Start | Max labelled | Steps to max |
|---|---|---|---|---|---|---|
| Zepbound Eli Lilly | Tirzepatide | Weight management | Weekly | 2.5 mg | 15 mg | 6 |
| Wegovy Novo Nordisk | Semaglutide | Weight management | Weekly | 0.25 mg | 2.4 mg | 5 |
| Rybelsus Novo Nordisk | Semaglutide (oral) | Type 2 diabetes | Daily | 3 mg | 14 mg | 3 |
Cost comparison calculator
Enter the quotes you have actually been given. Everything is normalised to cost per month and cost per milligram so the options are comparable.
Monthly requirement21.65 mg4.33 doses/month × 5 mg
| Option | Per month | Per year | Per mg | One unit lasts |
|---|---|---|---|---|
| Option A | — | — | — | — |
| Option B | — | — | — | 2.0 weeks |
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