Manufacturer direct-pay program
Both Lilly and Novo Nordisk run self-pay programs for people without coverage. Pricing tiers change frequently — check the official program page for current rates.
Tirzepatide dosage cost
You are trying to work out what this will cost you per month.
Reference and calculator, not medical advice. Dosing figures below are transcribed from FDA-approved prescribing information and link back to it. Last reviewed August 2026.
What Zepbound costs you depends on three things that have nothing to do with the sticker price: whether your plan covers tirzepatide for your indication, which supply route you use, and what dose you settle at. That last one matters more than people expect — Zepbound is dosed weekly, so monthly consumption scales directly with the step you are on.
Zepbound — how much you actually consume
Weekly dosing means about 4.33 doses a month. Quantity drives cost, so this is the table that decides your monthly bill.
| Dose | Per month | Per year | A 10 mg vial lasts |
|---|---|---|---|
| 2.5 mg | 10.82 mg | 130 mg | 4.0 weeks |
| 5 mg | 21.65 mg | 260 mg | 2.0 weeks |
| 7.5 mg | 32.48 mg | 390 mg | 1.3 weeks |
| 10 mg | 43.30 mg | 520 mg | 1.0 weeks |
| 12.5 mg | 54.13 mg | 650 mg | 0.8 weeks |
| 15 mg | 64.95 mg | 779 mg | 0.7 weeks |
Cost per milligram is the only figure that stays comparable across these rows. Enter your own quotes below to convert them onto that basis.
Cost comparison calculator
Enter the quotes you have actually been given. Everything is normalised to cost per month and cost per milligram so the options are comparable.
Monthly requirement21.65 mg4.33 doses/month × 5 mg
| Option | Per month | Per year | Per mg | One unit lasts |
|---|---|---|---|---|
| Option A | — | — | — | — |
| Option B | — | — | — | 2.0 weeks |
Where the price comes from
The routes people actually pay through, and what determines the number in each.
Through insurance (copay)
If your plan covers the drug for your indication, your cost is the plan copay. Coverage for weight-loss indications is far less common than for type 2 diabetes.
Telehealth platform (brand drug)
Online clinics bundle a prescriber visit with brand-name medication. Membership fee is usually separate from drug cost.
Compounded semaglutide / tirzepatide
Compounded versions are prepared by pharmacies rather than the original manufacturer. Availability and legality depend on FDA shortage status, which has changed several times — verify current status before relying on this route.
Retail pharmacy cash price
List price without insurance, sometimes reduced by discount cards.
Common questions
- Why do quoted GLP-1 prices vary so much?
- Because the quotes are not measuring the same thing. A membership fee, a per-vial price, and a per-pen price all describe different quantities, and the dose you are on determines how long that quantity lasts. Converting everything to cost per milligram is the only way to compare them directly.
- Does insurance usually cover this?
- Coverage is far more common for type 2 diabetes indications than for weight management. Whether your specific plan covers your specific indication is something only your plan documents can answer.
Sources and last review
Every dosing figure on this page is transcribed from an FDA-approved label and links back to it. Conversions are arithmetic you can repeat by hand. Nothing here is reviewed by a clinician, and this site does not employ one — which is exactly why what I do publish stays traceable to its source.
- Zepbound (Tirzepatide) prescribing information — Eli Lilly, label revised 6 May 2026, checked 7 August 2026
Transcribed from the labels above and checked by me — Gavin, who builds this site, takes a GLP-1, and is not a clinician. Last reviewed August 2026. Found an error? [email protected] — I treat corrections as bugs. How this site is built and funded.