GLP-1 dosage for weight loss

You are trying to work out how much to draw or when to step up.

Standard titration schedules for the main GLP-1 medications are shown below, taken from each product's prescribing information. Use the converter to translate a dose in milligrams into syringe units at a given concentration.

Side-by-side

Structural facts from each product’s prescribing information.

Product	Active ingredient	Indication	Frequency	Start	Max labelled	Steps to max
Zepbound Eli Lilly	Tirzepatide	Weight management	Weekly	2.5 mg	15 mg	6
Mounjaro Eli Lilly	Tirzepatide	Type 2 diabetes	Weekly	2.5 mg	15 mg	6
Wegovy Novo Nordisk	Semaglutide	Weight management	Weekly	0.25 mg	2.4 mg	5
Ozempic Novo Nordisk	Semaglutide	Type 2 diabetes	Weekly	0.25 mg	2 mg	4
Saxenda Novo Nordisk	Liraglutide	Weight management	Daily	0.6 mg	3 mg	5
Trulicity Eli Lilly	Dulaglutide	Type 2 diabetes	Weekly	0.75 mg	4.5 mg	4

mg → syringe units converter

U-100 syringe. Formula: (dose ÷ concentration) × 100.

MedicationDose (mg)

Vial concentration (mg/mL)

12.5units on a U-100 syringe

= 0.125 mL · 2.5 mg at 20 mg/mL

Check the concentration printed on the vial you are actually holding. The same dose in milligrams is a completely different mark on the syringe at a different concentration. If the number here does not match what your prescriber told you, trust your prescriber.

Dose escalation exists to reduce gastrointestinal side effects, not to reach a target faster. The schedules above are the labelled defaults — prescribers routinely hold patients at a step longer, and some people stay on a lower maintenance dose indefinitely. Any change to your own schedule is a decision for the person who wrote your prescription.

GLP-1 dosage for weight loss

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