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GLP-1 injection site

You are trying to work out how much to draw or when to step up.

Reference and calculator, not medical advice. Dosing figures below are transcribed from FDA-approved prescribing information and link back to it. Last reviewed August 2026.

The labels are specific and consistent on this: inject subcutaneously in the abdomen, thigh or upper arm. That instruction is identical across the weekly injectables, and rotating between sites is directed rather than optional.

The Ozempic label puts the rotation instruction plainly — use a different injection site each week when injecting in the same body region. Injection site reactions appear in the adverse-reaction tables for these products, and rotation is the labelled measure against them.

Listed in the prescribing information

Common adverse reactions listed for GLP-1 receptor agonists as a class.

These products carry a boxed warning regarding thyroid C-cell tumours observed in rodent studies, and are contraindicated in people with a personal or family history of medullary thyroid carcinoma or MEN 2. Read the full prescribing information for your specific product and discuss it with your prescriber — this summary is not complete and is not a substitute for that document.

One instruction that matters if you also take insulin: the labelling says to administer them as separate injections and never to mix the products. Injecting both in the same body region is acceptable, but the injections should not be adjacent.

mg → syringe units converter

U-100 syringe. Formula: (dose ÷ concentration) × 100.

12.5units on a U-100 syringe
= 0.125 mL  ·  2.5 mg at 20 mg/mL

Check the concentration printed on the vial you are actually holding. The same dose in milligrams is a completely different mark on the syringe at a different concentration. If the number here does not match what your prescriber told you, trust your prescriber.

Common questions

Does the site change how well it works?
The labels give three sites without ranking them, which is the answer. They do not describe one as more or less effective than another.
Why rotate at all?
Injection site reactions are listed among the adverse reactions for these products, and rotation is what the labelling directs to limit them.
What if I hit a blood vessel or it bleeds?
Minor bleeding happens and is not itself alarming. Anything beyond that, or a site that stays painful, swollen or hard, is worth showing to your prescriber rather than describing online.
Does this apply to compounded vials too?
The route is the same, but a compounded preparation has no label of its own. Follow the instructions that came with your prescription, and convert the dose against the concentration printed on the vial you are holding.

Sources and last review

Every dosing figure on this page is transcribed from an FDA-approved label and links back to it. Conversions are arithmetic you can repeat by hand. Nothing here is reviewed by a clinician, and this site does not employ one — which is exactly why what I do publish stays traceable to its source.

Transcribed from the labels above and checked by me — Gavin, who builds this site, takes a GLP-1, and is not a clinician. Last reviewed August 2026. Found an error? [email protected] — I treat corrections as bugs. How this site is built and funded.

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